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32-17(15)16(28)11(27)6-24)31-12-5-22-9-3-2-8(20)14(21)13(9)12
It is bioavailable in mice following ip administration
Sirtinol significantly decreases SIRT1 expression and increases the acetylated p53 level
including dysfunctional endosomal and endoplasmic reticulum-to-Golgi vesicle trafficking
Pullambhatla M
GAP-134 Hydrochloride etaminophen 32-17(15)16(28)11(27)6-24)31-12-5-22-9-3-2-8(20)14(21)13(9)12Danegaptide, also known as GAP 134 and ZP1609, is an orally active small molecule gap junction modifier for the treatment of atrial fibrillation. Danegaptide mproves conduction and reduces atrial fibrillation flutter in the canine sterile pericarditis model. Danegaptide prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia reperfusion injury in open chest dogs. Product information CAS Number: 943133 81 1