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amsacrine may induce transcription of tumor promoter p53 protein and block p53 ubiquitination and proteasomal degradation
and represses tumor growth
ISX9 is also shown to induce cardiomyogenic differentiation of Notch-activated epicardium-derived cells in vitro
No significant changes in body weights
Kenwood BM
AA-CW236 Size:Contact [email protected] for quotation amsacrine may induce transcription ofAA CW236 is a MGMT (O6 methylguanine DNA methyltransferase) inhibitor. AA CW236 targets MGMT active site Cys145 for covalent modification. Product information CAS Number: 1869921 96 9 Molecular Weight: 400. 78 Formula: C17H16ClF3N4O2 Smiles: CC1ON=C(C)C=1CCN1N=NC(=C1CCl)C1C=CC(=CC=1)OC(F)(F)F InChiKey: MPDMMSRZEHOFPA UHFFFAOYSA N InChi: InChI=1S C17H16ClF3N4O2 c1 10 14(11(2)27 23 10)7 8 25 15(9 18)16(22 24 25)12 3 5 13(6 4 12)26 17(19,20)21 h3 6H,7
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