TG-89 - inhibitor of JAK2, FLT3, RET and JAK3. CAS# 936091-56-4 NE-781 H2O/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16

H2O/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16

TDZD8 results in a significant decline of cellular ATP levels in PC-3 cells

Exendin-4 as a stimulator of rat insulin I gene promoter activity via bZIP/CRE interactions sensitive to serine/threonine protein kinase inhibitor Ro 31-8220

The combination therapy results in a significantly enhanced reduction in tumor volume when compared to either Sotrastaurin (AEB071) or BYL719 alone (p=0

CAS Number: 91531-30-5

TG-89 - inhibitor of JAK2, FLT3, RET and JAK3. CAS# 936091-56-4 NE-781 H2O/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16TG 89 is an inhibitor of JAK2 with IC50 of 11. 2 M. Product information CAS Number: 936091 56 4 Molecular Weight: 510. 65 Formula: C26H34N6O3S Chemical Name: N tert Butyl 3 [[5 methyl 2 [3 (morpholin 4 ylmethyl)anilino]pyrimidin 4 yl]amino]benzenesulfonamide Smiles: CC1=CN=C(NC2=CC(CN3CCOCC3)=CC=C2)N=C1NC1=CC(=CC=C1)S(=O)(=O)NC(C)(C)C InChiKey: OOSKXASFJFSOBK UHFFFAOYSA N InChi: InChI=1S C26H34N6O3S c1 19 17 27 25(29 21 8 5 7 20(15 21)18 32 11 13 35