AG-014699(PF-01367338) oc Malate 1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

Smiles: OC1=C(/C=N/NC(=O)CNC2=CC=C3C=CC=CC3=C2)C=C(Br)C(O)=C1Br

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

Chemical Name: N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3

Crew et al (2018) Identification and characterization of Von Hippel-Lindau-recruiting proteolysis targeting chimeras (PROTACs) of TANK-binding kinase 1

AG-014699(PF-01367338) oc Malate 1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoateRucaparib (AG014699) is an orally active and potent inhibitor of PARP with Ki of 1. 4 nM for PARP1 in a cell free assay. Rucaparib shows binding affinity to eight other PARP domains. Product information CAS Number: 283173 50 2 Molecular Weight: 323. 36 Formula: C19H18FN3O Synonym: AG 14699 AG014447 (as free base) PF 01367338 Rucaparib free base Rubraca Related CAS Number: 459868 92 9 (Rucaparib phosphate) 1859053 21 6 (Rucaparib Camsylate) Chemical