![JAK2/FLT3-IN-1 TFA 13224 Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCC#C)C(C)(C)C)=CC=1](https://cdn.shopify.com/s/files/1/0389/1897/9723/files/M34863_1743256150.gif?v=1743256150)
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Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCC#C)C(C)(C)C)=CC=1
AZD-8529 is a potent
Elgiushy HR
InChi: InChI=1S/C24H22ClN5O/c1-14-7-23(26)30-15(2)21(14)13-29-24(31)17-5-6-27-20(11-17)9-16-3-4-22-18(8-16)10-19(25)12-28-22/h3-8
CAS Number: 1619994-69-2
JAK2/FLT3-IN-1 TFA 13224 Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCC#C)C(C)(C)C)=CC=1JAK2 FLT3 IN 1 (TFA) is a potent and orally active dual JAK2 FLT3 inhibitor with IC50 values of 0. 7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. JAK2 FLT3 IN 1 (TFA) has anti cancer activity. Product information CAS Number: 2928093 29 0 Molecular Weight: 581. 61 Formula: C27H35F4N7O3 Chemical Name: 2 ({1 [2 fluoro 4 ({5 methyl 4 [1 (propan 2 yl) 1H pyrazol 4 yl]pyrimidin 2 yl}amino)phenyl]piperidin 4 yl}(methyl)amino)ethan 1