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Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties
nude mice) treatment enhances the effect of Sorafenib on inhibiting tumor growth in nude HCC-bearing mice model
VHL is one of the most popular E3 ligases being recruited by bifunctional PROTACs to induce ubiquitination and subsequent proteasomal degradation of a target protein
Smiles: ONC(=O)CCC1=CC=C(CN[C@@H](C2CCCCC2)C(=O)OC2CCCC2)C=N1
fattiness and grease
Raloxifene 6-glucuronide Catalog No.:M13237-10 Hippo coactivator YAP1 upregulates SOX9Raloxifene 6 glucuronide is a primary metabolite of Raloxifene. Raloxifene 6 glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6 glucuronide binds to estrogen receptor with an IC50 of 290 M. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGF3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element containing vitellogenin promoter expression. Product