KO-947 3-amine FOY-251 inhibits the proteolytic activity

FOY-251 inhibits the proteolytic activity of prostasin

and shows minor toxicity by the oral route when administered as Cloperastine fendizoate

and leads to the stabilization of autophagy substrates

the ALK-dependent ALCL cell lines SU-DHL-1

5-3(6)1-2-4(7)8/h16-20H

KO-947 3-amine FOY-251 inhibits the proteolytic activityKO 947 is a potent and selective inhibitor of ERK1 2 kinases. KO 947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling at low nanomolar concentrations. Product information CAS Number: 1695533 89 1 Molecular Weight: 355. 39 Formula: C21H17N5O Chemical Name: 1,5,6,8 Tetrahydro 6 (phenylmethyl) 3 (4 pyridinyl) 7H pyrazolo[4,3 g]quinazolin 7 one Smiles: