![SGX-523 - CAS# 1022150-57-7 Size:Solid 10 mg 3-c]pyridine-3](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M11158_1621563086.gif?v=1742888023)
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3-c]pyridine-3
The compound shows profound antiviral activity in murine and rat lethal challenge models of disseminated herpes
InChi: InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H
Molecular Weight: 400
BAY 61-3606 is a potent (Ki = 7
SGX-523 - CAS# 1022150-57-7 Size:Solid 10 mg 3-c]pyridine-3SGX523 is a novel, ATP competitive kinase inhibitor remarkable for its exquisite selectivity for MET. SGX523 potently inhibited MET with an IC50 of 4 nmol L and is >1,000 fold selective versus the >200 fold selectivity of other protein kinases tested in biochemical assays. Crystallographic study revealed that SGX523 stabilizes MET in a unique inactive conformation that is inaccessible to other protein kinases, suggesting an explanation for the