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Neratinib (HKI-272) vinostat) PubMed Central PMCID: PMC3717953

SKU: 7483869797

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Description

PubMed Central PMCID: PMC3717953

Formula: C21H14N2Na2O9S2

PubMed Central PMCID: PMC5672092

4(8):1189-1195

In the presence of LW8

Neratinib (HKI-272) vinostat) PubMed Central PMCID: PMC3717953Neratinib, also known as HKI 272 or PB272, is an orally available, irreversible inhibitor of the HER 2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER 2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP binding pocket of the receptor. Product information CAS Number: 698387 09 6 Molecular Weight: 557. 04 Formula: C30H29ClN6O3 Synonym:

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