IL-17A antagonist 1 15309 including cellular proliferation

including cellular proliferation

InChiKey: NVUJDKDVOZVALT-UHFFFAOYSA-N

Alsterpaullone also acts as a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 of both 4 nM for GSK-3α and GSK-3β

NGD-4715 was developed for the treatment of obesity

InChi: InChI=1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4

IL-17A antagonist 1 15309 including cellular proliferationIL 17A antagonist 1 (compound 1) is an IL 17A antagonist, with a Kd of 0. 66 M and an IC50 of 1. 14 M. Product information CAS Number: 2205034 18 8 Molecular Weight: 604. 71 Formula: C33H41FN6O4 Chemical Name: (2S) N {4 [2 (2 {1 [(dimethylcarbamoyl)methyl]cyclopentyl}acetamido)ethyl]phenyl} 3 (2 fluorophenyl) 2 [(1 methyl 1H pyrazol 5 yl)formamido]propanamide Smiles: CN(C)C(=O)CC1(CC(=O)NCCC2C=CC(=CC=2)NC(=O)[C@H](CC2=CC=CC=C2F)NC(=O)C2=CC=NN2C)CCCC1