and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more)
such as IFN-γ
CNT2 inhibitor-1 (compound 48) exhibits 81-fold more potent inhibitory activity than the parent compound 12
Lintitript is also very active (ED50 = 27 μg/kg p
Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases
N-Pivaloyl-L-tyrosine M-1-4a and is selective (1000-fold more)N Pivaloyl L tyrosine is an N pivaloyl amino acid ester. Product information CAS Number: 33019 85 1 Molecular Weight: 265. 30 Formula: C14H19NO4 Chemical Name: (2S) 2 (2,2 dimethylpropanamido) 3 (4 hydroxyphenyl)propanoic acid Smiles: CC(C)(C)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(O)=O InChiKey: SUQCHHVYBPOPTR NSHDSACASA N InChi: InChI=1S C14H19NO4 c1 14(2,3)13(19)15 11(12(17)18)8 9 4 6 10(16)7 5 9 h4 7,11,16H,8H2,1 3H3,(H,15,19)(H,17,18) t11 m0 s1 Technical