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ZXH-3-26 is a selective PROTAC BRD4 degrader
Kaempferol also has anti-inflammatory effects via inhibition of interleukin-4 and cyclo-oxygenase 2 expression by suppressing Src kinase and downregulating the NFκB pathway
The proliferation and transformation of the HCT15
InChiKey: AUMDBEHGJRZSOO-UHFFFAOYSA-N
which is also a PPARβ/δ target gene in skeletal muscle cells
Guggulsterone - CAS# 95975-55-6 Catalog No.:M12290-10 ZXH-3-26 is a selective PROTACGuggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl 1 A1, Bcl 2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist,
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