AKT-IN-VIII - CAS# 612847-09-3 size:Contact [email protected] for quotation 127(2):287-289

127(2):287-289

3791/51519

de Alwis DP

PubMed PMID: 20086151

3-(4-((3-methyl-2-butenyl)oxy)phenyl)-4-(2-methylpropyl)-

AKT-IN-VIII - CAS# 612847-09-3 size:Contact [email protected] for quotation 127(2):287-289AKT IN VIII, CAS No. 612847 09 3, also known as AKTi 1 2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKI activity and aryl hydrocarbon receptor pathway. AKT IN VIII suppresses hyperthermia induced Ndrg2 phosphorylation in gastric cancer cells. AKT IN VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium