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In human cervical explant cultures
Chemical Name: 4-[(E)-2-(5
is a potent and selective and orally active PRMT5 inhibitor with a half-maximal inhibitory concentration (IC50) of 22 nM and broad selectivity against a panel of other histone methyltransferases
3)17-8-6-4-5-7-9(8)10(13)16-11(14)15-7/h4-6H
(E)-DMU2105 (Compound 7k) shows 74 and 120-fold selectivity for CYP1B1 over CYP1A1 and CYP1A2
Ivacaftor-D9 Size:Contact [email protected] for quotation In human cervical explant culturesIvacaftor D9 (CTP 656) is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D F508del HBE Cells. Ivacaftor D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research. Product information CAS Number: 1413431 07 8 Molecular Weight: 401. 55 Formula: C24H28N2O3 Chemical Name: N {2 tert butyl 5 hydroxy 4 [2 (H)methyl(1,1,1,3,3,3 H)propan 2 yl]phenyl} 4 oxo 1,4 dihydroquinoline 3
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