Dovitinib-D8 zine-d3 Smiles: CC1=CC2C=C(C=CC=2N1)OC1C=CN=C(NC2=CC(CS(=O)(=O)NCCN(C)C)=CC=C2)N=1

Smiles: CC1=CC2C=C(C=CC=2N1)OC1C=CN=C(NC2=CC(CS(=O)(=O)NCCN(C)C)=CC=C2)N=1

InChi: InChI=1S/C15H17NO5/c17-15(20-13-6-4-2-1-3-5-7-13)21-14-10-8-12(9-11-14)16(18)19/h1-2

3-benzodiazol-5-yl}-2-methoxybenzamide

20)21)23-17(24-16)22-14-5-3-2-4-6-14

2015 Jun 20

Dovitinib-D8 zine-d3 Smiles: CC1=CC2C=C(C=CC=2N1)OC1C=CN=C(NC2=CC(CS(=O)(=O)NCCN(C)C)=CC=C2)N=1Dovitinib D8 (CHIR 258 D8) is the deuterium labeled Dovitinib. Dovitinib (CHIR 258) is a multi targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8 9, 10 13 8, 27 210 nM for FLT3, c Kit, FGFR1 FGFR3, VEGFR1 VEGFR2 VEGFR3 and PDGFR PDGFR, respectively. Product information CAS Number: 1246819 84 0 Molecular Weight: 400. 48 Formula: C21H21FN6O Chemical Name: 4 amino 5 fluoro 3 {6 [4 methyl(2,2,3,3,5,5,6,6 H)piperazin 1 yl] 1H 1,3 benzodiazol 2 yl}