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induces DNA double-strand breaks quantified as S139 phosphorylated histone foci (γ-H2AX) and Comet tails induced in MDA-MB-231 cells
Molecular Weight: 424
Smiles: CN1CCN(CC1)C1=C(F)C=C2C3=C1OCN(C)N3C=C(C(O)=O)C2=O
an increase in type II collagen and proteoglycans
Completo G
Tacrolimus Catalog No.:M7733-10 induces DNA double-strand breaks quantifiedTacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T lymphocyte signal transduction and IL 2 transcription. Immunosuppressive properties. Product information CAS Number: 104987 11 3 Molecular Weight: 804. 02 Formula: C44H69NO12 Synonym: FK 506 FK 506 FK506 fujimycin Prograf Protopic Advagraf Astagraf XL Related CAS Number: 109581 93 3