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1353900-92-1
ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13
tyrosine residues 877 and 1248 are dephosphorylated significantly by CI-1033 at a concentration of 3 μM or higher
A Phase I and pharmocokinetic study of exatecan mesylate administered as a protracted 21-day infusion in patients with advanced solid malignancies
Significant efficacy can be achieved with GS-9876 doses that produces trough pSYK inhibition of <50%
D-erythro-MAPP - CAS# 143492-38-0 16435 1353900-92-1D erythro MAPP (D e MAPP) is a ceramidase inhibitor, with an IC50 of 1 5 M in vitro. Product information CAS Number: 143492 38 0 Molecular Weight: 361. 56 Formula: C23H39NO2 Chemical Name: N [(1S, 2R) 1 hydroxy 1 phenylpropan 2 yl]tetradecanamide Smiles: C[C@@H](NC(=O)CCCCCCCCCCCCC)[C@@H](O)C1C=CC=CC=1 InChiKey: YLAZEWZHIRBZDA NFBKMPQASA N InChi: InChI=1S C23H39NO2 c1 3 4 5 6 7 8 9 10 11 12 16 19 22(25)24 20(2)23(26)21 17 14 13 15 18 21 h13 15,17
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