Licochalcone B 26-Dihydroxyvitamin D3 InChi: InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5

InChi: InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5

InChi: InChI=1S/C131H222N44O41/c1-60(2)43-81(120(209)174-100(66(13)14)103(135)192)153-95(184)53-149-106(195)77(31-35-93(133)182)158-116(205)84(46-63(7)8)166-118(207)85(47-64(9)10)164-110(199)75(29-23-41-147-130(140)141)155-112(201)78(32-36-94(134)183)160-117(206)83(45-62(5)6)162-109(198)73(27-21-39-145-128(136)137)154-104(193)67(15)152-122(211)89(55-176)170-114(203)80(34-38-98(188)189)159-108(197)74(28-22-40-146-129(138)139)156-115(204)82(44-61(3)4)163-111(200)76(30-24-42-148-131(142)143)157-123(212)91(57-178)171-119(208)86(48-65(11)12)165-113(202)79(33-37-97(186)187)161-124(213)92(58-179)172-127(216)102(69(17)181)175-121(210)87(49-70-25-19-18-20-26-70)168-126(215)101(68(16)180)173-96(185)54-150-107(196)88(51-99(190)191)167-125(214)90(56-177)169-105(194)72(132)50-71-52-144-59-151-71/h18-20

It also specifically inhibited kinase activity of the protein (IC50 = 370+/-120 pM)

40 mg/kg) maximally inhibits GARFT activity after at 6 hours and thereafter gradually increases with time but remains significantly lower than control even at 96 hours

small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity

Licochalcone B 26-Dihydroxyvitamin D3 InChi: InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5Licochalcone B is an extract from the root of Glycyrrhiza inflate. Licochalcone B inhibits amyloid (A42) self aggregation (IC50=2. 16 M) and disaggregate pre formed A42 fibrils, reduce metal induced A42 aggregation through chelating metal ions. Product information CAS Number: 58749 23 8 Molecular Weight: 286. 28 Formula: C16H14O5 Chemical Name: (2E) 3 (3,4 dihydroxy 2 methoxyphenyl) 1 (4 hydroxyphenyl)prop 2 en 1 one Smiles: COC1C( C=C