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InChi: InChI=1S/C21H26ClN5O2/c1-13-10-17(28)19-18(13)20(25-12-24-19)26-6-8-27(9-7-26)21(29)16(11-23)14-2-4-15(22)5-3-14/h2-5
12H2/b25-19+
Formula: C39H33N5O15S2
Formula: C14H16Cl2N2O5S
PubMed PMID: 24021571
PROTAC BRD4 Degrader-11 5-2 InChi: InChI=1S/C21H26ClN5O2/c1-13-10-17(28)19-18(13)20(25-12-24-19)26-6-8-27(9-7-26)21(29)16(11-23)14-2-4-15(22)5-3-14/h2-5PROTAC BRD4 Degrader 11 (compound 9a) is a PROTAC connected by ligands for von Hippel Lindau and BRD4. PROTAC BRD4 Degrader 11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0. 23 nM and 0. 38 nM, respectively. Product information Molecular Weight: 1292. 56 Formula: C61H75F2N9O12S4 Chemical Name: (2S,4R) 1 [(2S) 2 (11 {[8 (3,5 difluoropyridin 2 yl) 4 (methanesulfonylmethyl) 15
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