Hydroxy-Dynasore Catalog No.:M25683-C The significant occupancy proportion of

The significant occupancy proportion of the D2R (44-66%) is observed only at a dose of 60 mg/kg

Smiles: NC(=O)C1=CN=C(NCCC2=CC(Cl)=C(O)C=C2)N=C1NCC1C=CC=CC=1

once daily) significantly reduces the volume of tumor in mice bearing H1993 tumors

Chemical Name: 2-cyclopropyl-5-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1

InChiKey: AFDJSRZVXYKUQT-UHFFFAOYSA-N

Hydroxy-Dynasore Catalog No.:M25683-C The significant occupancy proportion ofHydroxy Dynasore (Dyngo 4a), a structural analog of Dynasore (HY 15304), is an potency improved, low cytotoxicity and nonspecific binding dynamin inhibitor with IC50 values of 0. 38 M and 2. 3 M for brain dynamin I and recombinant rat dynamin II, respectively. Hydroxy Dynasore inhibits dynamindependent endocytosis of transferrin with an IC50 of 5. 7 M in vitro. Product information CAS Number: 1256493 34 1 Molecular Weight: 338. 31 Formula: C18H14N2O5