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Chymase-IN-1 10740 Prunetin inhibited LPS-induced inflammatory cytokine

SKU: 83137101929

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Description

Prunetin inhibited LPS-induced inflammatory cytokine production and MUC5 AC expression and secretion by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells

Formula: C36H40N6O10

InChi: InChI=1S/C26H32N2O4/c1-26(2

CAS Number: 1049704-18-8

The first Lineweaver–Burk plot is constructed in the absence of inhibitor

Chymase-IN-1 10740 Prunetin inhibited LPS-induced inflammatory cytokineChymase IN 1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM. Product information CAS Number: 862090 74 2 Molecular Weight: 431. 83 Formula: C20H15ClNO4PS Chemical Name: [(5 chloro 1 benzothiophen 3 yl)[(naphthalen 2 yl)carbamoyl]methyl]phosphonic acid Smiles: OP(O)(=O)C(C1=CSC2=CC=C(Cl)C=C12)C(=O)NC1=CC2=CC=CC=C2C=C1 InChiKey: HUJXISJLAPAFBO UHFFFAOYSA N InChi: InChI=1S C20H15ClNO4PS c21 14

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