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BX-471 exhibits 250-fold selectivity for CCR1 over CCR2
as the digestive vacuole is known to be acidic (pH 4
InChi: InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45
S-salbutamol on guinea-pig skeletal muscles are due to the activity of the R-enantiomer
6-dimethylphenyl)piperidine-2-carboxamide hydrochloride
Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 BX-471 exhibits 250-fold selectivity forEpirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.
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