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2017 Nov 6
hSMG-1 kinase plays a dual role in a highly conserved RNA surveillance pathway termed nonsense-mediated RNA decay (NMD) and in cellular genotoxic stress response
Mouse xenograft studies shows that the combination of clinically relevant doses of CPT-11 and 9-ING-41 lead to greater antitumor effect than is observed with either agent alone
InChiKey: UDQTXCHQKHIQMH-KYGLGHNPSA-N
Reduced VEGF production
MC-Val-Ala-PAB-PNP - CAS# 1639939-40-4 0179 2017 Nov 6MC Val Ala PAB PNP is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 1639939 40 4 Molecular Weight: 651. 66 Formula: C32H37N5O10 Synonym: MC Val Ala PABC PNP Chemical Name: {4 [(2S) 2 [(2S) 2 [6 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)hexanamido] 3 methylbutanamido]propanamido]phenyl}methyl 4 nitrophenyl carbonate Smiles:
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