Fedratinib hydrochloride hydrate ((2S)-1 2-propanediol hydrate) Smiles: COC1=CC=C2C(OC(C)(C)C3=C4C(=CC=C23)C(=O)N(C2C=CC(=CC=2)C(=O)C2C=CC=CC=2)C4=O)=C1O

Smiles: COC1=CC=C2C(OC(C)(C)C3=C4C(=CC=C23)C(=O)N(C2C=CC(=CC=2)C(=O)C2C=CC=CC=2)C4=O)=C1O

Smiles: C[C@H]1C=C(C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@H]2CC[C@@H](O2)[C@H](O)CCCCCCCCCCCC)C(=O)O1

Formula: C15H18N2O

InChi: InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3

arzoxifene does not upregulate cathepsin D mRNA and protein expression

Fedratinib hydrochloride hydrate ((2S)-1 2-propanediol hydrate) Smiles: COC1=CC=C2C(OC(C)(C)C3=C4C(=CC=C23)C(=O)N(C2C=CC(=CC=2)C(=O)C2C=CC=CC=2)C4=O)=C1OFedratinib hydrochloride hydrate (TG 101348 hydrochloride hydrate) is a potent, selective, ATP competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35 and 334 fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research. Product information CAS Number: