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Formula: C17H14Cl2F2N2O3
Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53
1450655-76-1 (RS-CPI-169)
Vidya Iyer
Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9
IM-250 isantherin A Formula: C17H14Cl2F2N2O3IM 250 not only reduces the duration of disease symptoms or time to healing but also prevents recurrent disease in guinea pigs. Treatment of recurrent infections reduces the frequency of recurrences and viral shedding, and, unlike nucleosidic drugs, IM 250 remains effective for a time after cessation of treatment. Hence, IM 250 has advantages over standard of care therapies and represents a promising therapeutic for chronic HSV infection, including
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