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Mcl-1 inhibitor 6 (compound 40
InChi: InChI=1S/C20H24N10O13P2/c21-14-8-15(24-3-23-14)29(4-25-8)18-10(31)12-6(40-18)1-38-45(36
PLX647 dihydrochloride (30 mg/kg BID) is able to prevent bone damage by the tumor cells
In syngeneic 129S1 mice
H2O : 100 mg/mL (745
AES-350 - CAS# 847249-57-4 12841 Mcl-1 inhibitor 6 (compound 40AES 350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0. 0244 M and 0. 035 M, respectively. AES 350 is also against HDAC 3, 8, and 11 in an enzymatic activity assay with IC50 values of 0. 187 M, 0. 245 M, and >1M, respectively. AES 350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research. Product information CAS Number: 847249 57 4 Molecular Weight: 312. 36 Formula:
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