α-Hydroxyglutaric acid Size:Contact [email protected] for quotation RPMI8226 cells) treatment inhibits the

RPMI8226 cells) treatment inhibits the IL-6-induced interaction between TCF4 and β-catenin and the phosphorylation of TCF4

01-1000 nM

InChi: InChI=1S/C141H218N40O48/c1-16-68(10)111(135(222)154-56-102(192)151-57-103(193)160-94(61-183)119(206)153-59-105(195)159-93(50-101(148)191)139(226)180-42-26-34-96(180)133(220)163-81(33-23-25-41-143)121(208)177-112(71(13)185)137(224)157-70(12)116(203)165-89(49-100(147)190)130(217)175-110(67(8)9)140(227)181-43-27-35-97(181)134(221)164-83(37-39-99(146)189)123(210)179-114(73(15)187)141(228)229)176-122(209)82(36-38-98(145)188)162-125(212)85(45-65(4)5)167-126(213)87(47-75-54-150-79-31-21-20-30-77(75)79)171-138(225)113(72(14)186)178-131(218)90(51-106(196)197)158-104(194)58-152-118(205)84(44-64(2)3)166-132(219)95(62-184)173-120(207)80(32-22-24-40-142)161-115(202)69(11)156-124(211)86(46-74-28-18-17-19-29-74)168-127(214)88(48-76-55-149-63-155-76)169-128(215)91(52-107(198)199)170-129(216)92(53-108(200)201)172-136(223)109(66(6)7)174-117(204)78(144)60-182/h17-21

InChiKey: LLPBUXODFQZPFH-UHFFFAOYSA-N

Encenicline is a selective α7 nicotinic acetylcholine receptor agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease

α-Hydroxyglutaric acid Size:Contact [email protected] for quotation RPMI8226 cells) treatment inhibits theHydroxyglutaric acid (2 Hydroxyglutarate) is an hydroxy acid form of glutaric acid. Hydroxyglutaric acid is a competitive inhibitor of multiple ketoglutarate dependent dioxygenases, including histone demethylases and the TET family of 5 methlycytosine (5mC) hydroxylases. Product information CAS Number: 2889 31 8 Molecular Weight: 148. 11 Formula: C5H8O5 Chemical Name: 2 hydroxypentanedioic acid Smiles: OC(=O)CCC(O)C(O)=O InChiKey: HWXBTNAVRSUOJR