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Pimitespib
induces the reduction of BCR-ABL protein with a DC50 of 10 μM
The kinome selectivity profile of PF-06650833 (Compound 40) is assessed in a panel of 278 kinases (Invitrogen) at 200 nM inhibitor concentration using the ATP Km for each kinase
is activated upon DNA damage and plays a key role in repairing double-stranded DNA breaks via the DNA nonhomologous end joining (NHEJ) pathway
PubMed PMID: 25885811
Norcantharidin henanthrol PimitespibExtracted from Mylabris phalerata Pallas dry bulk; Store the product in sealed, cool and dry condition Product information CAS Number: 5442 12 6 Molecular Weight: 168. 15 Formula: C8H8O4 Chemical Name: 4,10 dioxatricyclo[5. 2. 1. 0,]decane 3,5 dione Smiles: O=C1OC(=O)C2C1C1CCC2O1 InChiKey: JAABVEXCGCXWRR UHFFFAOYSA N InChi: InChI=1S C8H8O4 c9 7 5 3 1 2 4(11 3)6(5)8(10)12 7 h3 6H,1 2H2 Technical Data Appearance: Solid Power Purity: 98% (or refer to the