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LPA2 antagonist 2 210676 1-4H3/b21-14+/t17

SKU: 8692030191

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Description

1-4H3/b21-14+/t17

InChi: InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11

55(2):766-82

(2009) Nat Struct Mol Biol

temperature (25-37 degrees C) and incubation time (2-30 min)

LPA2 antagonist 2 210676 1-4H3/b21-14+/t17LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28. 3 nM and a Ki of 21. 1 nM. LPA2 antagonist 2 is >480 fold more selective than LPA3 (IC50 of 13. 85 M). Product information CAS Number: 36840 10 5 Molecular Weight: 380. 35 Formula: C20H16N2O6 Chemical Name: (2E) 3 ({4' [(2E) 3 carboxyprop 2 enamido] [1,1' biphenyl] 4 yl}carbamoyl)prop 2 enoic acid Smiles: OC(=O) C=C C(=O)NC1C=CC(=CC=1)C1C=CC(=CC=1)NC(=O) C=C C(O)=O

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