(R)-CR8 - CAS# 294646-77-8 Size:2mg solid A fast and sensitive ultra-high-performance

A fast and sensitive ultra-high-performance liquid chromatography-tandem mass spectrometry method for determining mefentrifluconazole in plant- and animal-derived foods

InChi: InChI=1S/C18H19N3O7/c22-13-5-4-12(16(25)20-13)21-17(26)10-2-1-3-11(15(10)18(21)27)19-7-9-28-8-6-14(23)24/h1-3

DY131 could potentiate the ERRgamma-induced growth inhibition in LNCaP-ERRgamma and DU145-ERRgamma cells in a dose-dependent manner

InChi: InChI=1S/C17H25NO4

while high concentrations (1-3 g/L) produces a pronounced vasodilator after a transient vasocontraction

(R)-CR8 - CAS# 294646-77-8 Size:2mg solid A fast and sensitive ultra-high-performance(R) CR8 (CR8), a second generation analog of Roscovitine, is a potent CDK1 2 5 7 9 inhibitor. (R) CR8 inhibits CDK1 cyclin B (IC50=0. 09 M), CDK2 cyclin A (0. 072 M), CDK2 cyclin E (0. 041 M), CDK5 p25 (0. 11 M), CDK7 cyclin H (1. 1 M), CDK9 cyclin T (0. 18 M) and CK1 (0. 4 M). (R) CR8 induces apoptosis and has neuroprotective effect[1][2]. (R) CR8 acts as a molecular glue degrader that depletes cyclin K. Product information CAS Number: 294646 77 8