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shape change in basophils and chemotaxis of human eosinophils and Th2 cells with similar potency
Chemical Name: 5-(Methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile
4-f]quinoline-7-carboxamide
2S)-2-(aminomethyl)-N
14(15):1837-51
BMS-626529 Size:Solid 2 mg shape change in basophils andTemsavir, also known as BMS 626529, is a potent HIV 1 attachment inhibitor. BMS 663068 is also the phosphonooxymethyl prodrug of BMS 626529 that targets HIV 1 gp120 and prevents its binding to CD4(+) T cells. BMS 626529 had half maximal effective concentration (EC(50)) values of <10 nM against the vast majority of viral isolates; however, susceptibility varied by >6 log(10), with half maximal effective concentration values in the low pM range against
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