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CGP 35348 induced pain-like response to mechanical stimulation in a dose-dependent way and reduced the paw withdrawal threshold to pressure
5)1(6)7/h6-11
PDM2 (Compound 4b) exhibits a Ki of 1
PubMed Central PMCID: PMC3587237
Smiles: CN(CCCC(C#N)(C(C)C)C1C=C(OC)C(=CC=1)OC)CCC1C=C(OC)C(=CC=1)OC
MCC-555 Size:Contact [email protected] for quotation CGP 35348 induced pain-like responseMCC 555, also known as RWJ 241947, is a novel peroxisome proliferatoractivated receptor ligand . The PPAR receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism. It has been identified that PPAR is the major functional receptor for the thiazolidinedione class of insulin sensitizing drugs. The PPAR receptor is implicated in the processes of adipogenesis and systemic insulin
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