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NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv
(2′S)-4′-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranosylvisamminol exhibits weak anti-cancer activity in human cancer cell lines
with an IC50 value of 6 nM
a value similar to its in vitro blood gene induction potency
InChiKey: OPJZLUXFQFQYAI-UHFFFAOYSA-N
Melitracen hydrochloride Catalog No.:M23825-C NITD-349 is an MmpL3 inhibitorMelitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5 HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space. Product information CAS Number: 10563 70 9 Molecular Weight: 327. 89 Formula: C21H26ClN Chemical Name: [3 (10,10 dimethyl 9,10 dihydroanthracen 9 ylidene)propyl]dimethylamine
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