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PF-5006739 Size:Contact [email protected] for quotation enterovirus 71 (EV71) and human

SKU: 90953758525

4.6
USD120.00 USD147.00

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Description

enterovirus 71 (EV71) and human rhinovirus (HRV)

Santucci Z

CAS Number: 179113-91-8

33 mg/mL (325

InChi: InChI=1S/C23H11ClN4/c24-15-8-9-18-19(10-15)16-6-1-2-7-17(16)21-22(18)28-23(27-21)20-13(11-25)4-3-5-14(20)12-26/h1-10H

PF-5006739 Size:Contact [email protected] for quotation enterovirus 71 (EV71) and humanPF 5006739 is a potent and selective inhibitor of CK1 with IC50s of 3. 9 nM and 17. 0 nM, respectively. PF 5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1 and high kinome selectivity. PF 5006739 attenuats opioid drug seeking behavior in a rodent operant reinstatement model in animals in a dose dependent manner. PF 5006739 improves glucose tolerance in both diet induced obesity

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