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STM2457 is a highly potent and selective first-in-class catalytic inhibitor of METTL3
Chemical Name: (3S)-3-(aminomethyl)-4-chloro-7-(2-hydroxyethoxy)-1
Smiles: C/C=C(/C)\C(=O)O[C@@H]1C[C@@]2(C)O[C@@H]2C[C@H](OC(C)=O)C(C)=C[C@H]2OC(=O)C(=C)[C@H]12
a reversible and selective DGAT1 inhibitor with IC50 value of 80 nM
P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts
Agomelatine-d4 - CAS# 1079389-44-8 Catalog No.:M34906-C STM2457 is a highly potentAgomelatine d4 is the deuterium labeled Agomelatine. Agomelatine (S 20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0. 1, 0. 06, 0. 12, and 0. 27 nM for CHO hMT1, HEK hMT1, CHO hMT2, and HEK hMT2, respectively. Agomelatine is a selective 5 HT2C receptor antagonist with pKis of 6. 4 and 6. 2 at native (porcine) and cloned, human 5 HT2C receptors, respectively. Product information CAS Number: 1079389 44 8 Molecular Weight: 247. 33
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