GNE-8324 antolactone InChi: InChI=1S/C51H63F2N11O10/c1-54-51(70)61-17-11-41-40(31-61)47(62-14-3-4-32-26-37(33-29-56-59(2)30-33)38(46(52)53)28-43(32)62)58-64(41)35-9-15-60(16-10-35)45(66)12-18-71-20-22-73-24-25-74-23-21-72-19-13-55-34-5-6-36-39(27-34)50(69)63(49(36)68)42-7-8-44(65)57-48(42)67/h5-6

Name: GNE-8324 antolactone InChi: InChI=1S/C51H63F2N11O10/c1-54-51(70)61-17-11-41-40(31-61)47(62-14-3-4-32-26-37(33-29-56-59(2)30-33)38(46(52)53)28-43(32)62)58-64(41)35-9-15-60(16-10-35)45(66)12-18-71-20-22-73-24-25-74-23-21-72-19-13-55-34-5-6-36-39(27-34)50(69)63(49(36)68)42-7-8-44(65)57-48(42)67/h5-6
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SKU: 92727785232
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Description

InChi: InChI=1S/C51H63F2N11O10/c1-54-51(70)61-17-11-41-40(31-61)47(62-14-3-4-32-26-37(33-29-56-59(2)30-33)38(46(52)53)28-43(32)62)58-64(41)35-9-15-60(16-10-35)45(66)12-18-71-20-22-73-24-25-74-23-21-72-19-13-55-34-5-6-36-39(27-34)50(69)63(49(36)68)42-7-8-44(65)57-48(42)67/h5-6

Smiles: CN1C=C2C=C(C=CC2=N1)SC1=NN=C2C=CC(=NN21)C1C=NN(C)C=1

0075 and 0

Formula: C10H14N2O5

InChiKey: BNJOZDZCRHCODO-UHFFFAOYSA-N

GNE-8324 antolactone InChi: InChI=1S/C51H63F2N11O10/c1-54-51(70)61-17-11-41-40(31-61)47(62-14-3-4-32-26-37(33-29-56-59(2)30-33)38(46(52)53)28-43(32)62)58-64(41)35-9-15-60(16-10-35)45(66)12-18-71-20-22-73-24-25-74-23-21-72-19-13-55-34-5-6-36-39(27-34)50(69)63(49(36)68)42-7-8-44(65)57-48(42)67/h5-6GNE 8324 is a selective GluN2A positive allosteric modulator. GNE 8324 selectively enhances NMDA receptor (NMDAR) mediated synaptic responses in inhibitory but not excitatory neurons. Product information CAS Number: 1698901 76 6 Molecular Weight: 343. 42 Formula: C18H18FN3OS Chemical Name: 10 {[ethyl(4 fluorophenyl)amino]methyl} 7 thia 1,9 diazatricyclo[6. 4. 0. 0,]dodeca 2(6),8,10 trien 12 one Smiles: CCN(CC1=CC(=O)N2C(=N1)SC1CCCC2=1)C1C=CC(F)=CC=1

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