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even in dormant or nonreplicating mycobacteria
H520 and H460 cell lines are used
CAS Number: 75088-80-1
and bioavailabilities (F%) of 100 and 80%
which produced only extremely small amounts of Aβ42
Luotonin A NB 142-70 even in dormant or nonreplicatingIC50: 1. 8 g mL for P 388 cell line Luotonin A binds to and stabilizes the topoisomerase I DNA binary complex. Topoisomerase DNA complexes have been reported as the primary target of several important antitumor agents. These agents have been shown to be able to increase the number of topoisomerase associated DNA strand breaks in cells, by stabilizing the covalent enzyme DNA complex and therefore diminishing the resealing of the DNA phosphodiester
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