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InChi: InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-13-33-14-12-22-28-30-24(35-22)26-20(32)16-18-9-5-2-6-10-18/h1-10H
Smiles: CC(O)=C(C#N)C(=O)NC1=CC(Br)=CC=C1Br
Dacinostat exhausts in vitro self-renewal potential of murine AML1/ETO- and PLZF/RARα-positive HSC
It covalently binds to the cysteine 88 of ubiquitin receptor RPN13 in the 19S regulatory particle and inhibits proteasome function
conscious rats
Fluzoparib (SHR-3162) Size:10 mg solid InChi: InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-13-33-14-12-22-28-30-24(35-22)26-20(32)16-18-9-5-2-6-10-18/h1-10HFluzoparib (SHR3162, HS10160) is a potent Poly (ADP ribose) polymerase (PARP) inhibitor that shows anti tumor activity. Product information CAS Number: 1358715 18 0 Molecular Weight: 472. 40 Formula: C22H16F4N6O2 Chemical Name: 4 (4 fluoro 3 (2 (trifluoromethyl) 5,6,7,8 tetrahydro [1,2,4]triazolo[1,5 a]pyrazine 7 carbonyl)benzyl)phthalazin 1(2H) one Smiles: O=C1NN=C(CC2C=C(C(F)=CC=2)C(=O)N2CC3=NC(=NN3CC2)C(F)(F)F)C2=CC=CC=C12 InChiKey: XJGXCBHXFWBOTN
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