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JNK-IN-8 - CAS# 1410880-22-6 60136 (2012) Cancer Res

SKU: 94543328764

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Description

(2012) Cancer Res

InChiKey: ZCDBTQNFAPKACC-UHFFFAOYSA-N

Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors

24(2):167-176

InChiKey: OJXYMYYDAVXPIK-IWKNALKQSA-N

JNK-IN-8 - CAS# 1410880-22-6 60136 (2012) Cancer ResJNK IN 8, also known as JNK Inhibitor XVI, CAS No. 1410880 22 6, is a selective JNK inhibitor that inhibits phosphorylation of c Jun, a direct substrate of JNK, in cells exposed to submicromolar drug in a manner that depends on covalent modification of the conserved cysteine residue. Extensive biochemical, cellular, and pathway based profiling establish the selectivity of JNK IN 8 for JNK and suggests that the compound will be broadly useful as a

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