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20 hours) inhibits PRMT6 methyltransferase activity in HEK293 cells
Formula: C51H40N6O23S6
Chemical Name: (1-((6-(4-chlorophenoxy)pyridin-3-yl)methyl)-4-hydroxy-2-oxo-1
8(12):e83310
45(10):1626-32
N-(3-hydroxyphenyl)-Arachidonoyl amide isqualic acid 20 hours) inhibits PRMT6 methyltransferaseIC50: 2 M N (3 hydroxyphenyl) Arachidonoyl amide, also known as 3 HPAA, is an analog of AM404 (N (4 hydroxyphenyl) arachidonoyl amide), a selective inhibitor of carrier mediated transport of arachidonoyl ethanolamide. 3 HPAA, metabolized by both cyclooxygenase (COX) 1 and COX 2, is an irreversible and selective inhibitor of COX 2 with an IC50 value of 2 M. 3 HPAA can be efficiently oxygenated to prostaglandin and hydroxyeicosatetraenoate products by
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