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covalent inhibitor of phosphoinositide 3-kinases (PI3Ks) and Polo-Like kinase 1 (PLK1)
19-5-4-6-20(27)22(17)19)9-15(12-28(21)2)14-31-23(29)16-7-18(25)11-26-10-16/h4-7
InChi: InChI=1S/C19H23N3O3/c1-2-3-13-22(19(24)20-17-7-5-4-6-8-17)14-15-9-11-16(12-10-15)18(23)21-25/h4-12
total PKC-ζ
CC1=CC(N)=C2C=CC=CC2=[N+]1CCCCCCCCCC[N+]1=C2C=CC=CC2=C(N)C=C1C
TAK-071 olac covalent inhibitor of phosphoinositide 3-kinasesTAK 071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK 071 M1R agonist activities is 520 nM. Product information CAS Number: 1820812 16 5 Molecular Weight: 421. 46 Formula: C24H24FN3O3 Chemical Name: 4 fluoro 2 [(3S,4S) 4 hydroxyoxan 3 yl] 5 methyl 6 {[4 (1H pyrazol 1 yl)phenyl]methyl} 2,3 dihydro 1H isoindol 1 one Smiles:
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