UVI 3003 0071 Smiles: CN(C(CC1C=CC=CC=1)C(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21

Smiles: CN(C(CC1C=CC=CC=1)C(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21

25(5):644-53

such as H2AX

InChiKey: JZIQWNPPBKFOPT-LSYMHUITSA-N

selective and orally bioavailable EGFR tyrosine kinase inhibitor

UVI 3003 0071 Smiles: CN(C(CC1C=CC=CC=1)C(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR), and inhibits xenopus and human RXR in Cos7 cells, with IC50s of 0. 22 and 0. 24 M, respectively. Product information CAS Number: 847239 17 2 Molecular Weight: 436. 58 Formula: C28H36O4 Chemical Name: (2Z) 3 {4 hydroxy 3 [5,5,8,8 tetramethyl 3 (pentyloxy) 5,6,7,8 tetrahydronaphthalen 2 yl]phenyl}prop 2 enoic acid Smiles: CCCCCOC1=CC2=C(C=C1C1=CC(=CC=C1O) C=C\C(O)=O)C(C)(C)CCC2(C)C