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CEP-28122 mesylate salt Catalog No.:M20814-C 5R)-5-methyl-2-(propan-2-yl)cyclohexanecarbonyl]-2

SKU: 97921308268

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Description

5R)-5-methyl-2-(propan-2-yl)cyclohexanecarbonyl]-2

Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression

Although AM095 almost completely blocks histamine release (100 mg/kg)

Icariside F2 shows little or no cytotoxic activity by the MTT assay

BI-2852 is a potent inhibitor of KRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS

CEP-28122 mesylate salt Catalog No.:M20814-C 5R)-5-methyl-2-(propan-2-yl)cyclohexanecarbonyl]-2CEP 28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1. 9 nM for recombinant ALK kinase activity. CEP 28122 has antitumor activity in experimental models of ALK positive human cancers. CEP 28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity. Product information CAS Number: 2070009 30 0 Molecular Weight: 635. 17 Formula: C29H39ClN6O6S Chemical

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