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GSK-J4 hydrochloride Catalog No.:M15021-2 can induce apoptosis in cancer

SKU: 98430228605

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Description

can induce apoptosis in cancer cells

Epub 2011 Oct 6

InChi: InChI=1S/C15H23N5O2S/c1-16-23(21

Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor

CAS Number: 1290543-63-3

GSK-J4 hydrochloride Catalog No.:M15021-2 can induce apoptosis in cancerGSK J4 hydrochloride is a potent dual inhibitor of H3K27me3 me2 demethylases JMJD3 KDM6B and UTX KDM6A with IC50s of 8. 6 and 6. 6 M, respectively. GSK J4 hydrochloride inhibits LPS induced TNF production in human primary macrophages with an IC50 of 9 M. GSK J4 hydrochloride is a cell permeable prodrug of GSK J1. Product information CAS Number: 1797983 09 5 Molecular Weight: 453. 96 Formula: C24H28ClN5O2 Chemical Name: ethyl 3 {[2 (pyridin 2 yl) 6

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