Darbufelone mesylate 12748 fatty acid import into the

fatty acid import into the mitochondria and β-oxidation is reduced

InChiKey: JNDVEAXZWJIOKB-JYRVWZFOSA-N

compared to <6 for BIX01294

cell proliferation

EGFR-IN-5 is a EGFR inhibitor with IC50s of 10

Darbufelone mesylate 12748 fatty acid import into theDarbufelone mesylate (CI 1004 mesylate) is a dual inhibitor of cellular PGF2 and LTB4 production. Darbufelone potently inhibits PGHS 2 (IC50 = 0. 19 M) but is much less potent with PGHS 1 (IC50= 20 M). Product information CAS Number: 139340 56 0 Molecular Weight: 428. 57 Formula: C19H28N2O5S2 Synonym: CI 1004 mesylate Chemical Name: (5Z) 2 amino 5 [(3,5 di tert butyl 4 hydroxyphenyl)methylidene] 4,5 dihydro 1,3 thiazol 4 one; methanesulfonic acid