Lenalidomide-acetylene-C5-COOH 196moxiterol PDE5 inhibitors - pharmacology and

PDE5 inhibitors - pharmacology and clinical applications 20 years after sildenafil discovery

Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

53)31-11-4-3-10-30(31)54-2)24-20-22(21-25(34(24)28)37(44)49)12-16-32(46)41-19-6-5-18-40-27-9-7-8-23-35(27)39(51)45(38(23)50)29-15-17-33(47)42-36(29)48/h3-4

Smiles: C[C@@H]([C@@H](O)C1C=CC(O)=CC=1)N1CCC(CC2C=CC=CC=2)CC1

0 against all four PDE4 isoenzymes

Lenalidomide-acetylene-C5-COOH 196moxiterol PDE5 inhibitors - pharmacology andLenalidomide acetylene C5 COOH (compound 43; Cereblon ligand linker Conjugate) is the Lenalidomide based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide acetylene C5 COOH can be connected to the ligand for protein by a linker to form PROTAC. Product information CAS Number: 2429878 72 6 Molecular Weight: 382. 41 Formula: C21H22N2O5 Chemical Name: 8 [2 (2,6 dioxopiperidin 3 yl) 1 oxo 2,3 dihydro 1H isoindol 4 yl]oct 7 ynoic acid