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Structure of the NDH-2 - HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors
Treatment with Batimastat (60 mg/kg i
Sanapala KR
14(2):131-40
protein kinase B
Thailanstatin D nsin Structure of the NDH-2 -Thailanstatin D, an analogue of Thailanstatin A, is able to inhibit AR V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3' splice site. Thailanstatin D exhibits a potent tumor inhibitory effect on human CRPC xenografts leading to cell apoptosis. Product information CAS Number: 1609105 89 6 Molecular Weight: 519. 63 Formula:
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