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Tandospirone - CAS# 87760-53-0 Catalog No.:M10386-10 56(14):5675-90

SKU: 83078370502

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Description

56(14):5675-90

Smiles: CC(C)(C)C1C=CC(C=CC(=O)NC2=CC3OCCOC=3C=C2)=CC=1

Smiles: CC1=NC(C(=O)N2CCC[C@H]2CC2=NN=C(O2)C2C=CC=CC=2)=C(S1)C1=CC=CC=C1F

⁷]pentadeca-1(11)

XL-518 R-enantiomer

Tandospirone - CAS# 87760-53-0 Catalog No.:M10386-10 56(14):5675-90Tandospirone citrate is a potent and selective 5 HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR 2, SR 1C, 1, 2, D1 and D2 receptors (Ki values ranging from 1300 41000 nM). IC50 Value: 275 nM(Ki) Target: 5 HT1Ain vitro: Tandospirone is most potent at the 5 HT1A receptor, displaying a Ki value of 27 + 5 nM. The agent is approximately two to three orders of magnitude less potent at 5 HT2, 5 HT1C, alpha 1 adrenergic, alpha 2

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