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18)19)8-13(7-11)24-3/h4-10H
(2014) Nat Genet
30)31)6-7-18(16)25-20/h4-8
Epub 2014 Nov 7
female nude mice bearing HeyA8 tumors in the peritoneal cavity are randomly divided into 4 groups (n=10 per group): 1) vehicle orally twice daily and phosphate-buffered saline intraperitoneally weekly (control)
CGI-1746 - CAS# 910232-84-7 AA-94 18)19)8-13(7-11)24-3/h4-10HCGI1746 is a small molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto and transphosphorylation steps necessary for enzyme activation. Product information CAS Number: 910232 84 7 Molecular Weight: 579. 69 Formula: C34H37N5O4 Synonym: CGI1746 CGI 1746 Chemical Name: 4 tert butyl N [2 methyl 3 (4 methyl 6 {[4
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