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is an orally bioavailable inhibitor of monopolar spindle 1 (MPS1/TTK) kinase (IC50 = 1
CAS Number: 100427-26-7
2013 Oct 22
Specificity of polyclonal antibodies raised against a novel 24
25 µM) inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) and COX-2 levels
Asenapine Hydrochloride - CAS# 1412458-61-7 uorowillardiine hydrochloride is an orally bioavailable inhibitorAsenapine, also known as Org 5222 and HSDB 8061, shows high affinity (pKi) for numerous receptors, including the serotonin 5 HT1A (8. 6), 5 HT1B (8. 4), 5 HT2A (10. 2), 5 HT2B (9. 8), 5 HT2C (10. 5), 5 HT5A (8. 8), 5 HT6 (9. 5), and 5 HT7 (9. 9) receptors, the adrenergic 1 (8. 9), 2A (8. 9), 2B (9. 5), and 2C (8. 9) receptors, the dopamine D1 (8. 9), D2 (8. 9), D3 (9. 4), and D4 (9. 0) receptors, and the histamine H1 (9. 0) and H2 (8. 2) receptors.
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